LysetTM is manufactured by Sclavo Diagnostics International S.r.l. on Biorigen S.r.l. licence

BOOST YOUR CELL CULTURE TODAY FOR THE EXPERIMENTS OF TOMORROW

an “off the shelf”, fully standardized and lyophilized, human platelet derived cell culture supplement.

XENO-FREE COMPONENTS OF HUMAN ORIGIN

is being utilized to replace animal and human serum such as Fetal Bovine Serum (FBS) in culture medium formulation for different types of cells.

CELL SUPPLEMENT OBTAINED BY THE COMBINATION OF TWO COMPONENTS

the possibility of mixing the two supplement components (PL, human platelet lysate from Platelet Rich Plasma and AD, human Platelet Poor Plasma) in different percentages, allows the supplement customization and optimization for each cell type.

Platelets

Blood is a liquid tissue. Suspended in the watery plasma are three major types of cells and cell fragments: Red blood cells (RBCs) or erythrocytes, White blood cells (WBCs) or leukocytes and Platelets or thrombocytes. WBCs and Platelets are contained in the Buffy Coat obtained after blood centrifugation:

Source: Wikipedia (blood fractionation)

Biorigen uses the platelets included in the Buffy Coat as a source for manufacturing Lyset™.

Source: http://www.getwellnatural.com

Platelets circulate in the blood of mammals and play a fundamental role in tissue repair in hemostasis, leading to the formation of blood clots. This process is mainly due to growth factors which are present in the platelets (See after).

Herebelow are some facts about blood platelets:

  • Normal platelets counts in human blood range from 150’000/µL to 350’000/µL
  • Platelets or thrombocytes are regularly-shaped clear cell fragments, 2-3 µm in diameter. Storage at room temperature is limited to 5-7 days because of the risk of bacterial growth and loss of platelet functionality, as platelets do not tolerate refrigeration.